Diabetic retinopathy is a condition that may occur in people who have diabetes. It causes progressive damage to the retina, the light-sensitive lining at the back of the eye. Diabetic retinopathy is a serious sight-threatening complication of diabetes. Diabetes interferes with the body’s ability to use and store sugar (glucose). The disease is characterized by too much sugar in the blood, which can cause damage throughout the body, including the eyes. Over time, diabetes damages small blood vessels throughout the body, including the retina. Diabetic retinopathy occurs when these tiny blood vessels leak blood and other fluids. This causes the retinal tissue to swell, resulting in cloudy or blurred vision. The condition usually affects both eyes. The longer a person has diabetes, the more likely they will develop diabetic retinopathy. If left untreated, diabetic retinopathy can cause blindness.
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Symptoms of diabetic retinopathy include:
Diabetic retinopathy results from the damage diabetes causes to the small blood vessels located in the retina. These damaged blood vessels can cause vision loss:Fluid can leak into the macula, the area of the retina responsible for clear central vision. Although small, the macula is the part of the retina that allows us to see colors and fine detail. The fluid causes the macula to swell, resulting in blurred vision.
In an attempt to improve blood circulation in the retina, new blood vessels may form on its surface. These fragile, abnormal blood vessels can leak blood into the back of the eye and block vision.
Non-proliferative diabetic retinopathy (NPDR) is the early stage of the disease in which symptoms will be mild or nonexistent. In NPDR, the blood vessels in the retina are weakened. Tiny bulges in the blood vessels, called microaneurysms, may leak fluid into the retina. This leakage may lead to swelling of the macula.
Proliferative diabetic retinopathy (PDR) is the more advanced form of the disease. At this stage, circulation problems deprive the retina of oxygen. As a result, new, fragile blood vessels can begin to grow in the retina and into the vitreous, the gel-like fluid that fills the back of the eye. The new blood vessels may leak blood into the vitreous, clouding vision.
The below factors can also contribute to your Glaucoma progression.
Neuroprotection therapy helps protect neurons in your eye from injury such as from eye pressure elevations. Neurotrophins helps to provide the required neuroprotective therapy which prevents from death of the ganglion cells in your eyes.
Vascular dysregulation means that blood flow is not properly flowing. This causes reduced and unstable oxygen supply to the tissues in the eyes. This in turn causes a cacade of events causing glaucomatous optic neuropathy.
Oxidative stress damage is an important factor in development of glaucoma, which triggers trabecular meshwork degeneration, which then leads to intraocular hypertension. Different studies provide cumulating evidence, which supports the association of oxidative stress with different aspects of the neurodegenerative process happening in glaucoma.
Glaucoma is associated with toxic inflammatory factors leading to cell death and disease progression. Trabecular meshwork dysfunction is likely mediated by oxidative stress and inflammatory responses. Ocular surface inflammation may compromise the cornea, conjunctiva and the trabecular meshwork.
Excitotoxicity is increased levels of glutamate and is seen in Glaucoma patients which cause
retinal ganglion cell (RGC) death. If the toxic effects of glutamate aren't blocked, RGC loss can continue, leading to further visual impairment.
Netra Restoration Therapy provides the following benefits for patients with Glaucoma.
The level of loss of nerve fiber layer and optic nerve atrophy will determine the level of the improvement seen.
Most patients start to see subjective improvements in their vision within just 7 days of starting the NRT treatment.
NRT treatment can stop Glaucoma vision loss progression or considerably reduced to preserve the remaining vision.
NRT treatment improves visual field by reinstating dormant and sub-optimally functioning retinal cells. Without treatment these cells would eventually neurodegenerate and be lost forever.
With NRT treatment most glaucoma patients have shown improvement in their visual acuity by a minimum of 1 to 2 lines in distant and near vision.
Most glaucoma patients treated with NRT treatment have shown marked improvement in their color contrast.
Most glaucoma patients treated with NRT treatment have experienced having brighter vision, a reduction in glare, and blurry/cloudy vision.